Regenerative Medicine — Chatsworth, CA
PRP, PRF & Platelet-Derived
Growth Factor Therapy
Naya Wellness in Chatsworth offers all three generations of platelet-based regenerative treatment — from classic PRP to next-generation PDGF serum — for skin rejuvenation, hair restoration, and accelerated healing.
Your body’s own healing signal — now in a medical-grade formula
Platelet-Derived Growth Factor (PDGF) is a protein your body naturally produces whenever tissues need repair. It signals fibroblasts to produce collagen, tells blood vessels to grow, and activates the cellular machinery behind skin renewal and hair growth.
Unlike PRP or PRF — which concentrate your own platelets to release growth factors — PDGF therapy delivers a laboratory-purified, standardized dose of this key signaling protein directly, delivering consistent, predictable results every session.
- Stimulates collagen & elastin — activates fibroblasts for firmer, smoother skin
- Promotes angiogenesis — grows new blood vessels to nourish tissue and follicles
- Accelerates wound healing — speeds repair after laser, microneedling, or injury
- Reduces inflammation — calms post-procedure swelling and redness faster
- Activates stem cells — supports regenerative applications in aesthetics and orthopedics
- Standardized potency — same dose every session, regardless of your platelet count
PRP vs. PRF vs. PDGF — what’s the difference?
All three harness the power of growth factors to regenerate tissue. They differ in source, preparation, release profile, and consistency of results.
Blood is drawn and spun at high speed in a centrifuge to separate platelet-rich plasma. The concentrated plasma is re-injected or applied topically.
- Source Your own blood
- Release Rapid burst (days)
- Consistency Varies by patient
- Best for Hair restoration, skin refresh, post-procedure boost
Spun at a lower speed without additives. A fibrin clot forms naturally, trapping platelets, white blood cells, and stem cells in a gel matrix that releases growth factors slowly over weeks.
- Source Your own blood
- Release Slow & sustained (weeks)
- Consistency Moderate
- Best for Under-eye hollowing, fine lines, skin laxity
A lab-purified, medical-grade growth factor serum delivering a precise, high-concentration dose every session. No blood draw required. Consistent potency regardless of a patient’s individual biology.
- Source Lab-purified protein
- Prep time Minimal — no blood draw
- Release Targeted & sustained
- Consistency Standardized
- Best for Collagen remodeling, hair density, combination protocols
| Feature | PRP | PRF | PDGF — Next Gen |
|---|---|---|---|
| Requires blood draw | Yes | Yes | No |
| Growth factor concentration | Variable | Variable | Standardized |
| Fibrin scaffold (volume support) | No | Yes | No |
| Includes white blood cells | Low | Yes | N/A |
| Release timeline | Hours–days | Days–weeks | Targeted dosing |
| Session-to-session consistency | Low–moderate | Moderate | High |
| Suitable for combination Rx | Yes | Yes | Yes — excellent |
| Downtime | Minimal | Minimal | Minimal |
What can PDGF, PRP & PRF treat?
Platelet-based growth factor therapies are among the most versatile tools in regenerative aesthetics. Our Chatsworth providers match the right protocol to your specific goals.
Skin Rejuvenation & Anti-Aging
PDGF and PRP trigger collagen and elastin synthesis to reduce fine lines, improve texture, and restore a firm, radiant complexion. Often combined with microneedling for deeper delivery.
Hair Restoration
Growth factors stimulate dormant hair follicles, increase follicle diameter, and promote hair cycling. PRP has the longest clinical track record for hair loss; PDGF offers enhanced consistency.
Under-Eye Rejuvenation
PRF’s natural fibrin gel makes it ideal for the delicate tear-trough area — adding subtle volume and stimulating periorbital collagen without the risks of traditional filler.
Post-Procedure Recovery
Applied after laser resurfacing, chemical peels, or microneedling, PDGF and PRP accelerate skin healing, reduce inflammation, and shorten visible downtime.
Scar & Wound Healing
Growth factor therapy remodels scar tissue, improves skin tone and texture in acne scars, surgical scars, and stretch marks by driving organized collagen deposition.
Combination Regenerative Protocols
PDGF pairs powerfully with exosome therapy, Sculptra, peptides, and NAD+ — amplifying results across skin quality, volume, and cellular health simultaneously.
What to expect at your Naya Wellness Chatsworth appointment
Whether you choose PRP, PRF, or PDGF, your experience at our Chatsworth office follows a clear, comfortable process guided by a licensed medical provider.
Consultation & Goal-Setting
Your provider reviews your skin, hair, or tissue concerns, health history, and goals. Together you’ll choose the right treatment — or combination — and build your protocol.
Preparation
For PRP or PRF, a small blood draw is processed chairside. For PDGF, no blood draw is needed — the medical-grade serum is prepared quickly, saving time and discomfort.
Topical Numbing
A pharmaceutical-grade numbing cream is applied to the treatment area for 20–30 minutes to maximize your comfort during injection or microneedling delivery.
Treatment Delivery
Growth factors are delivered by micro-injection, microneedling channel infusion, or a combination. Sessions typically take 30–60 minutes depending on the treatment area.
Recovery & Follow-Up
Downtime is minimal. Mild redness or tenderness typically resolves within 24–48 hours. Most protocols recommend 3 initial treatments spaced 4 weeks apart.
Who is a good candidate for growth factor therapy?
Most healthy adults are candidates for PRP, PRF, or PDGF treatments. A consultation with a Naya Wellness Chatsworth provider is the best way to confirm eligibility.
✅ Good candidates typically include:
- Adults experiencing early signs of skin aging — fine lines, texture, dullness
- Patients with androgenic alopecia or diffuse hair thinning
- Those seeking to enhance or prolong results from other aesthetic treatments
- Patients with acne scarring or post-surgical scars
- Anyone wanting a natural, growth-factor-driven alternative to traditional injectables
- Patients wanting under-eye volume support without hyaluronic acid filler (PRF)
⚠️ Treatment may not be suitable for:
- Active skin infections, open wounds, or active acne at the treatment site
- Patients on blood thinners or with bleeding disorders (for PRP/PRF)
- Pregnancy or breastfeeding
- Active autoimmune or inflammatory conditions
- History of keloid scarring (discuss with your provider)
Your Naya Wellness provider will review your complete health history during your consultation to determine the safest, most effective protocol for you.
Common questions about PDGF, PRP & PRF
PRP (Platelet-Rich Plasma) uses your own blood, spun at high speed to concentrate platelets that release a burst of growth factors quickly. PRF (Platelet-Rich Fibrin) is spun at a lower speed without additives, creating a fibrin gel that releases growth factors slowly over days to weeks — and includes white blood cells and stem cells for added regenerative benefit. PDGF is a lab-purified, standardized growth factor protein — no blood draw needed, consistent potency every session, and ideal for patients who want predictable results or prefer to skip the blood draw.
Most protocols call for an initial series of 3 sessions spaced 4 weeks apart, followed by maintenance every 3–6 months. Some patients with hair loss or moderate skin laxity may benefit from 4–6 initial sessions. Your Naya Wellness provider will build a plan based on your goals and how your tissue responds after the first session.
PRP results typically begin appearing 2–4 weeks after treatment as collagen production ramps up. PRF’s slow-release fibrin matrix delivers more gradual improvements over 4–8 weeks, with peak results continuing to develop over 3 months. PDGF’s standardized high concentration often shows visible skin texture and firmness improvements within 4–6 weeks of a first session, with results building through the full treatment series.
PDGF used in aesthetic medicine is a highly purified, medical-grade protein studied extensively in wound healing and regenerative medicine. Side effects are typically mild and short-lived — slight redness, swelling, or tenderness at the injection site resolving within 24–48 hours. Your Naya Wellness provider will review your complete health history before any treatment to ensure it’s the right fit for you.
Yes — and combination protocols often produce the best outcomes. PDGF pairs particularly well with microneedling (for deeper dermal delivery), exosome therapy, Sculptra (for volumizing + biostimulation), laser resurfacing (to speed healing), NAD+ infusions, and peptide protocols. Your provider will recommend the optimal combination stack for your goals.
Both are effective. PRP has the largest body of clinical evidence for androgenic alopecia and is a proven first-line option. PDGF offers the advantage of standardized dosing — patients with low platelet counts or suboptimal plasma quality (which can affect PRP efficacy) often see more consistent results with PDGF. In many cases, providers recommend starting with PRP and stepping up to PDGF or combination therapy for enhanced outcomes.
Downtime is minimal for all three. You may experience mild redness, swelling, or pinpoint bruising at injection sites for 24–48 hours. If combined with microneedling, some pinpoint redness for 1–3 days is normal. Most patients return to normal activities the same day. Avoid intense sun exposure, saunas, and strenuous exercise for 24 hours post-treatment.
Ready to explore regenerative treatment
in Chatsworth?
Our licensed Chatsworth providers will help you choose between PRP, PRF, or PDGF — or design a combination protocol — tailored to your specific goals.
Naya Wellness · Chatsworth, CA · Licensed Medical Providers
This page is for informational purposes only and does not constitute medical advice. Individual results vary. Platelet-Derived Growth Factor, PRP, and PRF therapies should only be administered by licensed medical professionals following a comprehensive health evaluation. Always consult a qualified healthcare provider to determine whether these treatments are appropriate for your individual health status and goals.