Growth Hormone Support & Anti-Aging

CJC-1295 / Ipamorelin

1.5 mg CJC-1295 / 2.5 mg Ipamorelin per mL

The gold standard combination in growth hormone peptide therapy. CJC-1295 and Ipamorelin work synergistically to amplify your body's own GH production — supporting deeper sleep, body composition, recovery, and the markers of healthy aging.

Licensed clinicians U.S. compounding pharmacy Telehealth — no office visit

What to Expect

  • Weeks 1–2 Improved sleep quality and morning alertness
  • Weeks 2–4 Increased energy, improved recovery from exercise
  • Weeks 4–8 Noticeable lean mass gains, improved body composition
  • After your course Most patients hold gains and maintain improved sleep
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What is CJC-1295 / Ipamorelin?

CJC-1295 and Ipamorelin are two complementary peptides that together create a powerful growth hormone-stimulating effect. This combination is considered the gold standard in GH peptide therapy.

CJC-1295 is a synthetic GHRH (growth hormone-releasing hormone) analog — it signals your pituitary to release growth hormone.

Ipamorelin is a ghrelin mimetic — it amplifies GH release and simultaneously suppresses somatostatin, the hormone that shuts down GH production.

Together, they create a synergistic effect: more robust GH pulses, sustained signaling, and better overall results than either peptide alone.

How It Works

This dual-action combination works through your body's natural GH signaling:

  • CJC-1295 stimulates GHRH — directly signaling your pituitary to release growth hormone
  • Ipamorelin amplifies that signal — mimicking ghrelin to potentiate GH release
  • Ipamorelin suppresses somatostatin — removing the natural "off switch" for GH, extending the pulse
  • Synergistic effect — the combination produces a more pronounced GH response than either peptide alone

What Patients Use CJC-1295 / Ipamorelin For

This GH-supporting combination is used by patients seeking improved recovery, body composition, sleep quality, and markers of healthy aging.

Sleep Quality & Recovery

GH is released during deep sleep. This combination enhances natural sleep architecture and restorative sleep cycles.

Body Composition

Growth hormone supports lean mass and metabolic health. Patients often report improved muscle definition and reduced body fat.

Athletic Recovery

GH supports tissue repair, protein synthesis, and recovery between training sessions — ideal during active training phases.

Anti-Aging & Vitality

GH is associated with skin elasticity, joint health, and general sense of vitality — supporting healthy aging markers.

Metabolic Health

Growth hormone influences lipid profiles, glucose metabolism, and overall metabolic resilience.

Post-Surgical Healing

GH accelerates healing and recovery. Often used post-surgery with surgeon approval and clinical oversight.

Dosing Context

Your clinician will design your dosing protocol based on your goals, labs, age, and response. The information below is provided for context — your exact dosing will be prescribed at consultation.

Each 1 mL of your vial contains 1.5 mg CJC-1295 and 2.5 mg Ipamorelin, allowing flexibility for various protocols and titration schedules.

Most protocols involve subcutaneous injection in the evening, close to bedtime, to align with the natural GH pulse during sleep.

Typical Protocol Ranges

Administration
Subcutaneous injection
Typical Dose
100–200 mcg each peptide
Frequency
Once daily (evening)
Course Length
8–12 weeks minimum
Vial Concentration
1.5 mg / 2.5 mg per mL
Vial Size
5 mL

These are context ranges only. Your clinician will provide your personalized dosing instructions during consultation.

What to Expect

Growth hormone effects are cumulative — early changes are subtle but build over time. Most pronounced benefits appear by week 6–8.

  • Weeks 1–2
    Sleep and recovery signals

    Most patients notice improved sleep quality and deeper rest first. Morning alertness and recovery between workouts may improve early.

  • Weeks 2–4
    Energy and performance

    Increased daytime energy, improved workout performance, and faster recovery from exercise become apparent. Some report early body composition shifts.

  • Weeks 4–8
    Lean mass and definition

    The most pronounced benefits emerge during this window. Noticeable improvements in muscle definition, body composition, and recovery capacity.

  • After your course
    Sustained results

    Many patients hold their gains in body composition and sleep quality. Some opt for periodic courses (2–3 times per year) to maintain benefits, especially during active training phases.

Frequently Asked Questions

How is this different from Sermorelin?
Sermorelin is a single GHRH analog — it only stimulates GH release. CJC-1295 / Ipamorelin is dual-action: CJC-1295 provides GHRH stimulation, while Ipamorelin amplifies that signal and suppresses somatostatin (the hormone that shuts off GH). The result is a more robust, sustained GH response. Many clinicians consider CJC-1295 / Ipamorelin more effective than Sermorelin alone.
Is this as effective as injectable HGH?
Not identically — but for many patients, the benefits are substantial and the safety profile more favorable. This combination amplifies your body's own GH production. Injectable HGH is direct hormone replacement at pharmacological doses. The choice depends on your goals, baseline labs, and clinical judgment. Your clinician will discuss both options.
Does this suppress my natural GH production?
No. CJC-1295 / Ipamorelin works through your body's own signaling pathways to stimulate GH release — it doesn't suppress your baseline production. When you stop the peptides, your body returns to your baseline GH production.
Can I use this with other peptides?
Yes. This combination is often paired with BPC-157 or TB-500 for recovery enhancement, with GHK-Cu for skin and tissue remodeling, or with other performance or aesthetic peptides as part of a broader protocol. Your clinician will help design a comprehensive plan.
How is it administered?
Subcutaneous injection — a small injection just under the skin using a thin insulin needle. Most protocols are given in the evening, close to bedtime, to align with natural GH secretion during sleep. Self-administration at home is standard.
Are there side effects?
Generally well-tolerated. Mild injection site reactions (redness, slight tenderness) are common. Some patients report mild water retention or joint fluid changes (usually minor and reversible). Systemic side effects are uncommon. Discuss your health history with your clinician to identify any individual considerations.
Will this affect my IGF-1 levels?
Elevated GH typically leads to increased IGF-1 production — that's how much of GH's effects are mediated. Your clinician will monitor your IGF-1 levels during your course to ensure they remain in a healthy, physiological range. This is different from the supraphysiological IGF-1 levels seen with high-dose injectable HGH.
Is CJC-1295 / Ipamorelin FDA-approved?
No. These are prescribed off-label and prepared by licensed compounding pharmacies. Your clinician will discuss the regulatory status during your consultation. The use is based on clinical research and practitioner experience.

CJC-1295 / Ipamorelin vs. Sermorelin

Both support growth hormone. Here's how they compare:

FactorCJC-1295 / IpamorelinSermorelin
MechanismDual-action: GHRH + ghrelin mimetic + somatostatin suppressionSingle GHRH analog only
GH ResponseStronger, more sustained pulseModerate, shorter duration
Typical Results Timeline4–8 weeks for pronounced effects6–12 weeks for noticeable effects
FrequencyOnce daily (evening)Once or twice daily
Best ForPatients seeking faster, more robust results; active training phasesPatients preferring a gentler entry point; older patients
Cost ConsiderationsHigher due to dual peptideLower cost per course

Who Should Not Use CJC-1295 / Ipamorelin

This combination may not be appropriate for individuals who:

  • Are pregnant or breastfeeding
  • Have an active cancer diagnosis or recent cancer history (GH can promote cell growth)
  • Have uncontrolled diabetes (GH can affect glucose metabolism)
  • Have severe untreated sleep apnea (GH can exacerbate in some cases)
  • Have specific contraindications identified during clinical evaluation

Your clinician will review your full health history, labs (including baseline IGF-1), and medical status during consultation.

Ready to Optimize Your
Growth Hormone & Sleep?

Book a telehealth consultation with a Naya Wellness clinician. We'll review your goals, baseline labs, and health history to determine whether CJC-1295 / Ipamorelin is right for you.

No office visit required. Available via telehealth.

CJC-1295 and Ipamorelin are prescribed off-label and compounded by a licensed U.S. pharmacy for individual patients. Statements on this page have not been evaluated by the FDA. Results vary. Peptide therapy is not appropriate for everyone. This page is for informational purposes only and does not constitute medical advice. Consult a licensed clinician before starting any new therapy.

Medically reviewed by Carolyn Pampalone, MSN, FNP-BC · Last reviewed October 2026