At Naya, we offer Letybo®, a botulinum toxin type A injectable neuromodulator that effectively reduces the appearance of moderate to severe glabellar lines (frown lines). Letybo is designed for both women and men seeking a smoother, rejuvenated appearance without surgery or downtime.
Letybo (botulinum toxin type A) is an FDA-approved injectable treatment used to temporarily improve the appearance of glabellar lines, which are vertical lines that form between the eyebrows. It works by inhibiting acetylcholine release at the neuromuscular junction, causing temporary muscle relaxation in targeted areas.
Letybo was approved in the U.S. in 2023 and has been used internationally for over a decade. Clinical trials have demonstrated its safety, efficacy, and comparable performance to other botulinum toxins such as Botox and Dysport.
FDA-Approved for glabellar lines in adults
Natural, relaxed appearance without a frozen look
Starts working within 3–5 days
Results typically last 3–4 months
Well-tolerated in clinical trials
Letybo offers a refined formulation with high purity and consistent diffusion, making it ideal for patients who want a predictable, subtle result—especially those new to neuromodulators or seeking alternatives to Botox.
Women typically seek Letybo for a smoother, softer, and more youthful facial appearance. At Naya Aesthetics, we focus on individualized treatment plans that respect natural movement and preserve femininity while reducing the appearance of lines and wrinkles.
Men often desire a more refreshed yet masculine look. Letybo can reduce furrowed brows or tired appearance without softening distinct male facial features. Our providers are experienced in adjusting dosage and injection patterns to meet the anatomical and aesthetic needs of male patients.
Yes. Letybo has been extensively studied in Phase III clinical trials for FDA approval and demonstrated non-inferior efficacy to Botox [2]. The most common side effects include mild headache, injection site pain, and temporary eyelid drooping in rare cases—similar to other botulinum toxins.
We conduct a full consultation to determine if Letybo is the right choice for you, especially if you have underlying health conditions or prior sensitivities to botulinum toxin products.
While Letybo, Botox, and Dysport all contain botulinum toxin type A, Letybo is manufactured using proprietary purification techniques that ensure high purity and consistent performance. Some patients find it offers softer diffusion and more natural expressions, particularly in the glabella region.
Letybo is a great choice for both new patients and those who’ve experienced antibody resistance or tolerance to other brands.
Treatment Time: 10–20 minutes
Downtime: None (you may resume normal activity immediately)
Full Results: 5 to 10 days post-treatment
Maintenance: Every 3–4 months
Most patients describe Botox injections as a mild pinch. A topical numbing agent may be used for added comfort. Side effects are rare and typically limited to mild swelling, bruising, or tenderness at the injection site.
Common treatment goals for men include:
Soften deep frown lines without feminizing the face
Lift tired brows to appear more alert
Reduce crow’s feet for a more youthful gaze
Jawline contouring (masseter reduction for jaw slimming)
Men often prefer a subtle, refreshed look, and our providers are trained to deliver just that.
Board-certified providers with extensive facial anatomy training
Customized treatment plans for natural-looking results
Safe, medical-grade environment
We take a conservative, artful approach to Neurotoxins—our goal is to help you look like the best version of yourself.
Ready to smooth wrinkles, boost confidence, and reveal a refreshed look? Contact Naya today to schedule your appointment.
Letybo is a newer neurotoxin approved for use in the United States, originally developed in Korea. It works similarly to Botox and Dysport by relaxing facial muscles to smooth dynamic wrinkles.
Letybo is competitively priced at Naya Aesthetics. Schedule a consultation to discuss whether Letybo is right for your goals and get personalized pricing.
Minimal downtime. Return to your normal routine immediately. Avoid strenuous exercise, hot baths, and saunas for 24 hours.
Results appear within 5-7 days, peak around two weeks, and last approximately 3-4 months with regular treatments.
Yes, Letybo is FDA-approved and proven safe and effective for smoothing facial wrinkles. It is not suitable for pregnant or nursing women or patients with neuromuscular conditions.
Letybo is a Korean-developed alternative with comparable results to Botox and Dysport. Some patients report subtle differences in spread and longevity.
Side-by-side reads from the Naya editorial team.
Naya Wellness now offers Letybo at our Santa Barbara clinic — serving Montecito, Goleta & the South Coast.
View Letybo in Santa Barbara